hrp0092rfc3.4 | Multi-system Endocrine Disorders | ESPE2019

Peripheral Glucocorticoid Metabolim May Reflect Resolution of Inflammation in Kawasaki Disease

Sai Shuji , Tamura Takuya , Nagumo Kiyoshi , Chapman Karen

Background: Kawasaki disease (KD) is an acute inflammatory disorder, associated with systemic vasculitis including coronary artery aneurysms (CAA). Treatment with intravenous immunoglobulin (IVIG) can resolve inflammation. However, about 20% patients show resistant to IVIG treatment and some of the cases required additional treatments. Recently, IVIG plus adjuvant glucocorticoid hormones (GC) has been shown to be an effective therapy for these patients, su...